morphogens in a sentence
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- However, most morphogens are secreted proteins that signal between cells.
- Morphogens typically act through binding to specific protein Hedgehog, and ephrins.
- Those gradients have development significances akin to the gradients of morphogens in animal bodies.
- Some of the earliest and best-studied morphogens are transcription factors that signal between cells.
- Morphogens are soluble molecules that can diffuse and carry signals that control cell differentiation via concentration gradients.
- Sonic hedgehog ( Shh ) are morphogens that are essential to early patterning in the developing embryo.
- On the basis of the above work, it seemed likely that morphogens were present in the bone matrix.
- As there are no cell boundaries in the syncytium, these morphogens can influence nuclei in a concentration-dependent manner.
- Well-known morphogens include : decapentaplegic / transforming growth factor beta, Wnt, epidermal growth factor, and fibroblast growth factor.
- The organizing role that morphogens play during animal development was acknowledged in the 2014 naming of a new beetle genus, " Morphogenia ".
- It's difficult to see morphogens in a sentence .
- These morphogens are crucial for development, and include bone morphogenetic proteins, transforming growth factors ( TGFs ), and fibroblast growth factors ( FGFs ).
- Typically, morphogens are produced by source cells and diffuse through surrounding tissues in an embryo during early development, such that concentration gradients are set up.
- Thus, secreted morphogens act to generate gradients of transcription factor activity just like those that are generated in the syncitial " Drosophila " embryo.
- Some of the earliest and best-studied morphogens are transcription factors that diffuse within early " Drosophila melanogaster " ( fruit fly ) embryos.
- This definition concerns the mechanism, not any specific chemical formula, so simple compounds such as retinoic acid ( the active metabolite of retinol or vitamin A ) may also act as morphogens.
- In most developmental systems, such as human embryos or later " Drosophila " development, syncytia occur only rarely ( such as in skeletal muscle ), and morphogens are generally secreted signalling proteins.
- The discovery of Hox gene codes in flies and vertebrates has largely vindicated Wolpert's positional-value concept, while identification of growth-factor morphogens in many species has supported the concept of positional information.
- It allows free diffusion of transcription factors in a massive syncytium whereas almost anything else uses morphogens passed between separate cells to create that pattern indirectly ) talk ) 14 : 21, 10 December 2014 ( UTC)
- The molecular mechanism of bone induction studied by Professor Reddi led to the conceptual advance in tissue engineering that morphogens / metabologens bound to an insoluble extracellular matrix scaffolding act in collaboration to stimulate stem cells to form cartilage and bone.
- It is now known that Cripto is similar to other morphogens originating from the primitive streak in that it is asymmetrically expressed, specifically in a proximal-distal gradient, explaining the failure of posterior structures to form in the absence of Cripto.
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