hemoglobinopathy in a sentence

• Either hemoglobinopathy or thalassemia, or both, may cause anemia.
• Thus, some hemoglobinopathies are also thalassemias, but most are not.
• Hemoglobinopathies imply structural abnormalities in the globin proteins themselves.
• It is one of the most prevalent hemoglobinopathies with 30 million people affected.
• Certain hemoglobinopathies, the most common of which is sickle cell trait, do this.
• Other causes of splenomegaly ( for example, Gaucher disease or hemoglobinopathies ) can also predispose to infarction.
• The other forms of the disease require a pre-existing medical condition, usually associated with thalassemic hemoglobinopathy.
• Some mutations in the globin chain are associated with the hemoglobinopathies, such as sickle-cell disease and thalassemia.
• If both parents carry a hemoglobinopathy trait, the risk is 25 % for each pregnancy for an affected child.
• Early identification of individuals with sickle cell disease and other hemoglobinopathies allows treatment to be initiated in a timely fashion.
• It's difficult to see hemoglobinopathy in a sentence .
• This conference was preceded by a one-day workshop on " Fundamental Approaches in Molecular Diagnosis of Hemoglobinopathies ".
• His early research focused on retroviral vector based gene correction of hematopoietic cells from monogenetic disorders, such as hemoglobinopathies.
• Some well-known hemoglobin variants such as sickle-cell anemia and congenital dyserythropoietic anemia are responsible for diseases, and are considered hemoglobinopathies.
• Anemia of chronic disease, hereditary spherocytosis, hereditary hemoglobinopathies ( including some cases of thalassemia minor ) may all present with a normal RDW.
• In patients with diseases that reduce red blood cell lifespan, such as hemolytic anaemia or hemoglobinopathies because abnormal hemoglobin variants can interfere in the analysis.
• The two conditions may overlap, however, since some conditions which cause abnormalities in globin proteins ( hemoglobinopathy ) also affect their production ( thalassemia ).
• However, many hemoglobin variants do not cause pathology or anemia, and thus are often not classed as hemoglobinopathies, because they are not considered pathologies.
• In practice, fructosamine is rarely measured clinically ( even in individuals with hemoglobinopathies or other red cell disorders ) due to a number of pragmatic concerns.
• Differences in allele frequencies contribute to group differences in the incidence of some Ashkenazi Jewish populations ), or geographical ( hemoglobinopathies among people with ancestors who lived in malarial regions ).
• Some hemoglobinopathies ( and also related diseases like glucose-6-phosphate dehydrogenase deficiency ) seem to have given an evolutionary benefit, especially to heterozygotes, in areas where malaria is endemic.