calcifediol in a sentence

• The relationship between serum calcifediol level and all-cause mortality is parabolic.
• In the liver, vitamin D was found to be converted to calcifediol.
• In the liver, cholecalciferol ( vitamin D 3 ) is converted to calcifediol.
• Orally administered vitamin D produces rapid hepatic delivery of vitamin D and increases plasma calcifediol.
• Cholecalciferol is then hydroxylated in the liver to become calcifediol ( 25-hydroxyvitamin D 3 ).
• The enzyme catalyzes the hydroxylation of Calcifediol to calcitriol ( the bioactive form of Vitamin D ):
• Low blood calcifediol ( 25-hydroxy-vitamin D ) can result from avoiding the sun.
• Calcifediol is then converted by the kidneys to calcitriol, the biologically active form of vitamin D.
• At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.
• Vitamin D is carried in the bloodstream to the liver, where it is converted into the prohormone calcifediol.
• It's difficult to see calcifediol in a sentence .
• Circulating calcifediol may then be converted into calcitriol, the biologically active form of vitamin D, in the kidneys.
• Vitamin D oral supplementation and skin synthesis have a different effect on the transport form of vitamin D, plasma calcifediol concentrations.
• The only way to quantify adequate levels of vitamin D is with a serum 25 ( OH ) D 3 ( calcifediol ) test.
• Calcifediol is then hydroxylated in the kidney, and becomes calcitriol ( 1, 25-dihydroxyvitamin D 3 ) or active vitamin D 3.
• "' Calcifediol "'( vitamin D 3 ( cholecalciferol ) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F . Holick.
• Whether it is made in the skin or ingested, cholecalciferol is hydroxylated in the liver at position 25 ( upper right of the molecule ) to form 25-hydroxycholecalciferol ( calcifediol or 25 ( OH ) D ).
• The conversion of calcifediol to calcitriol is catalyzed by the enzyme 25-hydroxyvitamin D 3 1-alpha-hydroxylase, the levels of which are increased by parathyroid hormone ( and additionally by low calcium or phosphate ).
• Calcitriol ( 1, 25-dihydroxyvitamin D 3 ), the active metabolite of vitamin D 3, after being synthesized from calcifediol in the kidney, increases glutathione levels in the brain and appears to be a catalyst for glutathione production.
• It follows that an increase in vitamin D 3 intake should lead to a decrease in bone resorption & mdash; it has been shown that oral administration of vitamin D does not linearly correlate to increased serum levels of calcifediol, the precursor to calcitriol.
• Part of the calcifediol is converted by the kidneys to calcitriol, the biologically active form of vitamin D . Calcitriol circulates as a hormone in the blood, regulating the concentration of calcium and phosphate in the bloodstream and promoting the healthy growth and remodeling of bone.