cord factor in a sentence

• Cord factor also binds and activates the related C-type lectin MCL.
• Furthermore, the ester linkages in cord factor are important for its toxic effects.
• Upon activation by cord factor, Mincle binds the Fc receptor FcR? and Syk.
• Numerous responses that vary in effect result from cord factor's presence in host cells.
• After exposure to cord factor for 2 hours, 125 genes in the mouse genome are upregulated.
• There is evidence that cord factor is recognized by the Mincle receptor, which is found on macrophages.
• Cord factor has been observed to influence immune responses, induce the formation of granulomas, and inhibit tumor growth.
• When macrophages are activated by cord factor, they can arrange into granulomas around " M . tuberculosis " cells.
• Cord factor influences the arrangement of " M . tuberculosis " cells into long and slender formations, giving its name.
• Cord factor, through the Mincle receptor, also causes the recruitment of neutrophils, which lead to pro-inflammatory cytokines as well.
• It's difficult to see cord factor in a sentence .
• Cord factor also increases NADase activity in the host, and thus it lowers NAD; enzymes that require NAD decrease in activity accordingly.
• Cord factor is virulent towards mammalian cells and critical for survival of " M . tuberculosis " in hosts, but not outside of hosts.
• It is possible to form cord factor liposomes through water emulsion; these liposomes are nontoxic and can be used to maintain a steady supply of activated macrophages.
• Cord factor under proper control can potentially be useful in fighting cancer because IL-12 and IFN-? are able to limit the growth of tumors.
• Furthermore, cord factor's production of TNF-?, also known as cachectin, is also able to induce cachexia, or loss of weight, within hosts.
• "' Cord factor "', or trehalose dimycolate, is a glycolipid molecule found in the cell wall of " Mycobacterium tuberculosis " and similar species.
• Macrophage inducible Ca 2 +-dependent lectin, ( abbreviated to "'mincle "'), is a member of the C-type lectin superfamily encoded by the gene CLEC4E . It is a receptor for mycobacterial cord factor, trehalose-6, 6'- dimycolate ( TDM ).
• Cord factor presence increases the production of the cytokines interleukin-12 ( IL-12 ), interleukin-1 beta ( IL-1? ), interleukin-6 ( IL-6 ), tumor necrosis factor ( TNF? ), and macrophage inflammatory protein-2 ( MIP-2 ), which are all pro-inflammatory cytokines important for granuloma formation.