succinimidyl in a sentence

1. "' Carboxyfluorescein succinimidyl ester "'( CFSE ) is a fluorescent cell staining dye.
2. The spontaneous age-dependent degradation of l-aspartyl residue results in the formation of a succinimidyl intermediate.
3. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources.
4. "' Carboxyfluorescein diacetate succinimidyl ester "'( CFDA-SE ) is a micromolar are typically sufficient to give strong staining with minimal cell death.
5. For protein labeling, Cy3 and Cy5 dyes sometimes bear typically a succinimidyl group to react with amines, or a maleimide group to react with a sulfhydryl group of cysteine residues.
6. It's difficult to find succinimidyl in a sentence.
7. A succinimidyl-ester functional group attached to the fluorescein core, creating " NHS-fluorescein ", forms another common amine reactive derivative that has much greater specificity toward primary amines in the presence of other nucleophiles.
8. To prevent the accumulation of L-isoaspartyl, this residue is methylated by the protein L-isoaspartyl O-methyltransferase, which catalyzes the formation of a methyl ester, which in turn is converted back to a succinimidyl intermediate.
9. CFSE is commonly confused with carboxyfluorescein diacetate succinimidyl ester ( CFDA-SE ), although they are not strictly the same molecule; CFDA-SE, due to its acetate groups, is highly cell permeable, while CFSE is much less so.
10. CD36 function in long-chain fatty acid uptake and signaling can be irreversibly inhibited by sulfo-N-succinimidyl oleate ( SSO ), which binds lysine 164 within a hydrophobic pocked shared by several CD36 ligands, e . g . fatty acid and oxLDL.
11. SMCC, or succinimidyl " trans "-4-( maleimidylmethyl ) cyclohexane-1-carboxylate, is a " heterobifunctional crosslinker ", a type of chemical reagent that contains two reactive functional groups, a succinimide ester and a maleimide.