succinimide in a sentence
- Once all " N "-bromosuccinimide ( which is denser than the solvent ) has been converted to succinimide ( which floats on top ) the reaction has finished.
- Alternative routes include the partial hydrogenation of succinimide and the carbonylation of allylamine with methyl amine . 2-Pyrrolidone is an intermediate in the production of vinylpyrrolidone and the drug piracetam.
- The C-terminal residue of the intein domain is always an asparagine, which cyclizes to form a succinimide, cleaving its own peptide bond and releasing the intein from the extein.
- :the dienophile in the similar compound is maleic anhydride, which leads to a succinic anhydride derivative . the dienophile in your DA reaction is methyl maleimide, which leads to a succinimide derivative.
- The deamidation of a glutamine residue may proceed via the same mechanism but at a much slower rate since formation of the six-member-ring glutarimide intermediate is less favoured than the succinimide intermediate for asparagine.
- It's difficult to find succinimide in a sentence.
- The cleavage mechanism consists in the C-terminal peptide bond to the main chain forming a new bond to create a stable succinimide, cleaving itself from the main chain and consequently releasing the two halves of the product.
- In the deamidation of an asparagine residue under physiological conditions, the side chain is attacked by the nitrogen atom of the following peptide group ( in black at top right of Figure ), forming an asymmetric succinimide intermediate ( in red ).
- The succinimide group of SMCC reacts with the free amino group of a lysine residue in the trastuzumab molecule and the maleimide moiety of SMCC links to the free sulfhydryl group of DM1, forming a covalent bond between the antibody and the DM1.
- "' Succinimide "'is an organic compound with the formula ( CH 2 ) 2 ( CO ) 2 NH . This white solid is used in a variety of organic syntheses, as well as in some industrial silver plating processes.
- SMCC, or succinimidyl " trans "-4-( maleimidylmethyl ) cyclohexane-1-carboxylate, is a " heterobifunctional crosslinker ", a type of chemical reagent that contains two reactive functional groups, a succinimide ester and a maleimide.
- It is formed via a chemical reaction in which the nitrogen atom of the following peptide group ( in black at top right of Figure 1 ) nucleophilically attacks the ?-carbon of the side chain of an asparagine or aspartic acid residue, forming a symmetric succinimide intermediate ( in red ).
- If the succinimide ring is deleted so as to leave only the-NH 2 group attached to the benzene ring ( as in the alkaloid anthranoyllycoctonine, which also occurs naturally ), the resulting compound is intermediate between MLA and lycoctonine in potency and toxicity : it is less acutely toxic than MLA by a factor of about 4, but its affinity for 125 I-?-bungarotoxin binding sites is over 200x lower than that of MLA.