oxazaborolidine in a sentence
- The first step of the mechanism involves the coordination of BH 3 to the nitrogen atom of the oxazaborolidine CBS catalyst "'1 " '.
- The catalytic, asymmetric reduction of ketones may be accomplished through the use of catalytic amounts of an oxazaborolidine catalyst in conjunction with borane or catecholborane as the stoichiometric reducing agent.
- The oxazaborolidine reagent which mediates the enantioselective reduction of ketones was previously developed by the laboratory of Itsuno and thus this transformation may more properly be called the Itsuno-Corey oxazaborolidine reduction.
- The oxazaborolidine reagent which mediates the enantioselective reduction of ketones was previously developed by the laboratory of Itsuno and thus this transformation may more properly be called the Itsuno-Corey oxazaborolidine reduction.
- This catalyst, developed by Itsuno and Elias James Corey, is generated by heating ( " R " )-( + )-2-( diphenylhydroxymethyl ) pyrrolidine along with chiral oxazaborolidine catalysts has been used in the synthesis of commercial drugs such as ezetimibe and aprepitant.
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