canine disease in a sentence

1. Since 1989, scientists have identified and characterized 21 specific canine disease genes, half of them since 1996, and markers have been found for others, according to Patterson.
2. Although most dogs can easily tolerate the strain of leptospirosis that has traditionally been a canine disease, strains that " jump " from wild animals such as rats, mice and raccoons can be deadly.
3. It's difficult to find canine disease in a sentence.