t tubule meaning

  "t tubule" in a sentence
  • [Medicine]
    n : any of the small tubules which run transversely through a striated muscle fiber and through which electrical impulses are transmitted from the sarcoplasm to the fiber's interior


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  1. In between two terminal cisternae is a tubular infolding called a transverse tubule ( T tubule ).
  2. In skeletal muscle, the T tubule, an extension of the skeletal muscle plasma membrane, is located here.
  3. T tubules are the pathways for action potentials to signal the sarcoplasmic reticulum to release calcium, causing a muscle contraction.
  4. A stimulus, in the form of positively charged current, is transmitted from the neuromuscular junction down the length of the T tubules, activating dihydropyridine receptors ( DHPRs ).
  5. The sarcoplasmic reticulum serves as reservoir for calcium ions, so when an action potential spreads over the T tubule, it signals the sarcoplasmic reticulum to release calcium ions from the gated membrane channels to stimulate a muscle contraction.

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