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parkinson's disease meaning

Pronunciation:
  • Noun: Parkinson's disease
    1. A degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination
      - paralysis agitans, Parkinsonism, Parkinson's syndrome, Parkinson's, shaking palsy

    Type of: brain disease, brain disorder, degenerative disorder, encephalopathy

    Encyclopedia: Parkinson's disease


  • [Medicine]
    A progressive,degenerative neurologic disease characterized by a TREMOR that is maximal at rest,retropulsion (i.e. a tendency to fall backwards),rigidity,stooped posture,slowness of voluntary movements,and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE,DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al.,Principles of Neurology,6th ed,p1059,pp1067-75) n : a chronic progressive nervous disease chiefly of later life that is linked to decreased dopamine production in the substantia nigra and is marked by tremor and weakness of resting muscles and by a shuffling gait —called also paralysis agitans, parkinsonian syndrome, parkinsonism, Parkinson's, Parkinson's syndrome

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