oxalobacter formigenes meaning

  "oxalobacter formigenes" in a sentence
The sole species of the genus Oxalobacter consisting of straight or curved gram-negative rods with rounded ends. Cells are nonmotile,nonsporing,and use OXYLATES as the only source of CARBON and energy,with formate and CARBON DIOXIDE as end products. They are isolated from lake sediments and from the rumen or large bowel of humans and animals. (From Bergey's Manual of Determinative Bacteriology,9th ed)


  1. Despite their similarities, only oxalyl-CoA decarboxylase is necessary for the formation of ATP in " Oxalobacter formigenes ", and exogenous ADP has been demonstrated to increase the decarboxylase activity of OXC, but not acetolactate synthase.
  2. Oxalyl-CoA decarboxylase is extremely important for the elimination of ingested oxalates found in human foodstuffs like coffee, tea, and chocolate, and the ingestion of such foods in the absence of " Oxalobacter formigenes " in the gut can result in kidney disease or even death as a result of oxalate poisoning.

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