multiple exostosis meaning

[Medicine]
Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign,bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.

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