map kinase kinase kinase meaning

  "map kinase kinase kinase" in a sentence
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).


  1. This gene encodes a protein that belongs to the MAP kinase kinase kinase ( MAPKKK ) family of protein kinases.
  2. Aurora A phosphorylation directs the cytoplasmic polyadenylation translation of mRNA's, like the MAP kinase kinase kinase protein MOS, that are vital to the completion of meiosis in Xenopus Oocytes.
  3. The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7 / TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1.

Related Words

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