lymphocyte transformation meaning

  "lymphocyte transformation" in a sentence
Morphologic alteration of small lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS,MITOGENS such as PHYTOHEMAGGLUTININS,and by specific antigens. It may also occur in vivo,as in GRAFT REJECTION and chronic myelogenous leukemia (LEUKEMIA,MYELOID,CHRONIC).n : a transformation caused in lymphocytes by a mitosis-inducing agent (as phytohemagglutinin) or by a second exposure to an antigen and characterized by an increase in size and in the amount of cytoplasm, by visibility of nucleoli in the nucleus, and after about 72 hours by a marked resemblance to blast cells


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  1. effect of jieyongkang on lymphocyte transformation
  2. time effect of restraint stress-induced suppression of lymphocyte transformation
  3. effect of medicated thread moxibustion of zhuang folk medicine on lymphocyte transformation rate and rbc immunologic function in model rats of spleen deficiency
  4. methods : take the hemonlysin, phagocytic activity of peritoneal macrophages and lymphocyte transformation as the target to determine the immunity function
  5. the immunomodulatory effects of crude product were detected by lymphocyte transformation test ( lit ) and plaque forming cell assay ( pfc)

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