lymphocyte homing receptors meaning

  "lymphocyte homing receptors" in a sentence
Cell surface glycoproteins on lymphocytes and other leukocytes that mediate adhesion to specialized blood vessels called high endothelial venules. Several different classes of lymphocyte homing receptors have been identified,and they appear to target different surface molecules (addressins) on high endothelial venules in different tissues. The adhesion plays a crucial role in the trafficking of lymphocytes.


  1. While this may be the case to some extent, it is now widely held that the main driver in lymphocyte homing is the interactions between T cell adhesion molecules ( lymphocyte homing receptors ) and ligands ( addressins ) on the tissue high endothelial venules ( HEVs ).

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