lymphocyte activation meaning

  "lymphocyte activation" in a sentence
Morphologic alteration of small lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS,MITOGENS such as PHYTOHEMAGGLUTININS,and by specific antigens. It may also occur in vivo,as in GRAFT REJECTION and chronic myelogenous leukemia (LEUKEMIA,MYELOID,CHRONIC).


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  1. The peripheral lymphoid organs are the sites of lymphocyte activation by antigens.
  2. T-cell exhaustion is mediated by several inhibitory receptors including lymphocyte activation gene 3 protein ( LAG3 ).
  3. The defect in lymphocyte activation and protective immunity suggested that caspase-8 had additional signaling roles in lymphocytes.
  4. This gene encodes a member of the cytoprotective function that is essential for lymphocyte activation as well as cell survival.
  5. The "'signalling lymphocyte activation molecule family "'( SLAMF ) of innate and adaptive immune responses.

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