kb cell meaning
This line KB is now known to be a subline of the ubiquitous KERATIN-forming tumor cell line HeLa. It was originally thought to be derived from an epidermal carcinoma of the mouth,but was subsequently found,based on isoenzyme analysis,HeLa marker chromosomes,and DNA fingerprinting,to have been established via contamination by HELA CELLS. The cells are positive for keratin by immunoperoxidase staining. KB cells have been reported to contain human papillomavirus18 (HPV-18) sequences.
- This dye conjugate, DMTHF-DyLight 680, showed affinity for FR-� on KB cells, confirming the researchers'previous results.
- Since then its absolute configuration has been elucidated and callystatin A was discovered to have anti-fungal and anti-tumor activities with extreme potency against the human epidermoid carcinoma KB cells ( IG 50 = 10 pg / ml ) and the mouse lymphocytic leukemia Ll210 cells ( IG 50 = 20 pg / ml ).