histocompatibility antigen dna probes meaning

[Medicine]
DNA probes specific for the human leukocyte antigen genes,which represent the major histocompatibility determinants in humans. The four known loci are designated as A,B,C,and D. Specific antigens are identified by a locus notation and number,e.g.,HLA-A11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g.,insulin-dependent diabetes mellitus).

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