cord factor meaning
[Medicine]
Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.
Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.
Examples
More: Next- Cord factor also binds and activates the related C-type lectin MCL.
- Furthermore, the ester linkages in cord factor are important for its toxic effects.
- Upon activation by cord factor, Mincle binds the Fc receptor FcR� and Syk.
- Numerous responses that vary in effect result from cord factor's presence in host cells.
- After exposure to cord factor for 2 hours, 125 genes in the mouse genome are upregulated.
