classical complement pathway meaning
- [Medicine]
The sequential activation of complement,initiated by antigen-antibody complex and the binding of complement factor C1q to the Fc region of the antibody.
More: Next- The binding of XNAs initiate complement activation through the classical complement pathway.
- Three biochemical pathways activate the complement system : the classical complement pathway, the alternative complement pathway, and the lectin pathway.
- Three biochemical pathways activate the complement system : the classical complement pathway, the alternate complement pathway, and the mannose-binding lectin pathway.
- MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor.
- All pathways culminate in the production of a C3 convertase, which catalyses C3 into its constitutive parts ( better detailed here-classical complement pathway ).