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classical complement pathway meaning

  "classical complement pathway" in a sentence
  • [Medicine]
    The sequential activation of complement,initiated by antigen-antibody complex and the binding of complement factor C1q to the Fc region of the antibody.

Examples

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  1. The binding of XNAs initiate complement activation through the classical complement pathway.
  2. Three biochemical pathways activate the complement system : the classical complement pathway, the alternative complement pathway, and the lectin pathway.
  3. Three biochemical pathways activate the complement system : the classical complement pathway, the alternate complement pathway, and the mannose-binding lectin pathway.
  4. MASP-2 is very similar to the C1s molecule, of the classical complement pathway, and they are thought to have a common evolutionary ancestor.
  5. All pathways culminate in the production of a C3 convertase, which catalyses C3 into its constitutive parts ( better detailed here-classical complement pathway ).

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PC Version