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cell cycle regulatory proteins meaning

  "cell cycle regulatory proteins" in a sentence
  • [Medicine]
    Proteins that control the CELL DIVISION CYCLE. This family of proteins includes a wide variety of classes,including CYCLIN-DEPENDENT KINASES,mitogen-activated kinases,CYCLINS,and phosphoprotein phosphatases (PHOSPHOPROTEIN PHOSPHATASE) as well as their putative substrates such as chromatin-associated proteins,CYTOSKELETAL PROTEINS,and TRANSCRIPTION FACTORS.

Examples

  1. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle ( supplied by OMIM ).
  2. Wee1 protein is a tyrosine kinase that normally phosphorylates the Cdc2 cell cycle regulatory protein ( the homolog of CDK1 in humans ), a cyclin-dependent kinase, on a tyrosine residue.

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