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cd4 receptors meaning

  "cd4 receptors" in a sentence
  • [Medicine]
    55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes,but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors,binding directly to the envelope protein gp120 on HIV.

Examples

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  1. The structures are known to researchers as the CD4 receptor and the chemokine receptor.
  2. CD4 receptor ) on the target cell.
  3. On surfaces of helper T cells are CD4 receptors, as well as T cell receptors ( TCRs ).
  4. These cells express a CD4 receptor, to which HIV can bind, through the gp120 and gp41 proteins on its surface.
  5. One notable feature seen in the new pictures is that part of the CD4 receptor pokes into a large cavity inside the probe.

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