cd4 antigen meaning

  "cd4 antigen" in a sentence
55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes,but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors,binding directly to the envelope protein gp120 on HIV.
  • cd4:    Noun: CD4A glycopr ...
  • cd4 antigens:    [Medicine]55-kD Gl ...
  • cd4 cell:    Noun: CD4 cellT ce ...


  1. HIV belongs to the class of viruses called retroviruses, which carry genetic information in the form of RNA . HIV infects T cells that carry the CD4 antigen on their surface.

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