bioavailabilities meaning

  "bioavailabilities" in a sentence
[Medicine]
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.

Examples

  1. There is some debate about the different bioavailabilities of the different calcium salts.
  2. According to regulations applicable in the European Economic Area two medicinal products are bioequivalent if they are pharmaceutically equivalent or pharmaceutical alternatives and if their bioavailabilities after administration in the same molar dose are similar to such a degree that their effects, with respect to both efficacy and safety, will be essentially the same.
  3. Birkett ( 2003 ) defined bioequivalence by stating that, " two pharmaceutical products are bioequivalent if they are pharmaceutically equivalent and their bioavailabilities ( rate and extent of availability ) after administration in the same molar dose are similar to such a degree that their effects, with respect to both efficacy and safety, can be expected to be essentially the same.

Related Words

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  6. bioavailability meaning
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