b subunit alpha crystallin meaning

[Medicine]
One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS,CRYSTALLINE),alpha-crystallin B chain has been found in a variety of tissues such as HEART,BRAIN,MUSCLE and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.