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acquired-immune deficiency syndrome dementia complex meaning

  • [Medicine]
    A neurologic condition associated with the ACQUIRED IMMUNONDEFICIENCY SYNDROME and characterized by impaired concentration and memory,slowness of hand movements,ATAXIA,incontinence,apathy,and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefication,perivascular infiltrates of lymphocytes,foamy macrophages,and multinucleated giant cells. (From Adams et al.,Principles of Neurology,6th ed,pp760-1; N Engl J Med,1995 Apr 6;332(14):934-40)

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