cd4 receptors meaning
55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes,but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors,binding directly to the envelope protein gp120 on HIV.
- The structures are known to researchers as the CD4 receptor and the chemokine receptor.
- CD4 receptor ) on the target cell.
- On surfaces of helper T cells are CD4 receptors, as well as T cell receptors ( TCRs ).
- These cells express a CD4 receptor, to which HIV can bind, through the gp120 and gp41 proteins on its surface.
- One notable feature seen in the new pictures is that part of the CD4 receptor pokes into a large cavity inside the probe.