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bromodeoxyuridine meaning

Pronunciation:   "bromodeoxyuridine" in a sentence
  • [Medicine]
    or 5-bro·mo·de·oxy·ur·i·dine n : a mutagenic analog C9H11O5NBr of thymidine that induces chromosomal breakage esp. in heterochromatic regions and has been used to selectively destroy actively dividing cells —abbr. BUdR

Examples

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  1. In the label-retention assay, the goal is to mark'immortal'or parental DNA strands with a DNA label such as tritiated thymidine or bromodeoxyuridine ( BrdU ).
  2. In the Princeton study, Gould and her team injected monkeys with a compound called bromodeoxyuridine, or BRDU, that is taken up by cells in the process of making new cells.
  3. Thus, a cell lacking TK is resistant to bromodeoxyuridine ( BrdU ) and a cell lacking HGPRT is resistant to 6-thioguanine ( 6-TG ) and 8-azaguanine.
  4. In a range of between three weeks and two years before their deaths, the patients _ ages 55 to 70, in both early and advanced stages of the disease _ were given injections of bromodeoxyuridine ( BrdU ), a chemical marker, or tracer to help determine later what was happening in the hippocampus.

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