oxaloacetates meaning

• [Medicine]
  Salts and esters of oxaloacetic acid.

• The oxaloacetate level in the mitochondria is determined by the redox state.
• It is an important anaplerotic reaction that creates oxaloacetate from pyruvate.
• Oxaloacetate will be catalysed by PEPC-K to generate phosphoenolpyruvate.
• For example, oxaloacetate is formed by malate dehydrogenase within the mitochondrion.
• Oxaloacetate is the first substrate to bind to the enzyme.
• It is involved in the production of oxaloacetate from pyruvate.
• For example, glutamate can generate oxaloacetate in 2 steps.
• Finally, phosphoenolpyruvate carboxykinase ( PEPCK ) converts oxaloacetate to phosphoenolpyruvate ( PEP ).
• Similar to pyruvate carboxylase, PEP carboxylase replenishes oxaloacetate in the citric acid cycle.
• Once in the cytosol, aspartate is converted by cytosolic aspartate aminotransferase to oxaloacetate.

• "oxaloacetates" meaning in Chinese: n. 丁酮二酸盐或酯；草酰乙酸盐或酯